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Yueyue Li¹, Liebin Huang², Lin Li³

¹Medical Imaging Center, The First Affiliated Hospital of Jinan University, 510700 Guangzhou, Guangdong, China.

Discovery medicine

|October 28, 2024

概括

计算机断层扫描 (CT) 输液体积可以在手术前评估胃癌的淋巴血管入侵 (LVI). 平均传输时间 (MTT) 和流量提取产品 (FEP) 是LVI的独立预测指标,它们的组合显示出更好的诊断性能.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
医疗成像医学成像

背景情况:

彻底的手术是切除胃癌的主要治疗方法,但低生存率仍然存在.
淋巴血管侵袭 (LVI) 是胃癌 (GC) 复发和不良预后的关键预测因素.
目前通过组织学进行的LVI评估是术后的,并且受到活检异质性的限制.

研究的目的:

评估CT体积输液在胃癌中评估淋巴血管入侵 (LVI) 的疗效.
为了确定CT输液参数,可以预测GC患者的LVI.

主要方法:

59名GC患者进行CT体积输液和胃切除术的前性研究.
与LVI相关的临床病理变量和CT输液参数 (TTS,MTT,Tmax,FEP) 的分析.
进行了单变量,多变量逻辑回归和ROC分析.

主要成果:

在LVI阳性和LVI阴性组之间TTS,MTT,Tmax和FEP的显著差异.
确定了MTT和FEP作为LVI的独立预测因子 (p < 0.05).
与单个参数相比,MTT和FEP组合显示出更高的AUC (0.797) 和灵敏度 (84.62%).

结论:

CT体积输液是胃癌术前LVI评估的一个有价值的工具.
MTT和FEP是LVI的独立预测因素.
MTT和FEP的组合为LVI检测提供了卓越的诊断性能.

关键词:

电脑断层扫描X射线扫描腺癌瘤是一种腺癌.胃癌胃癌是一种胃癌.淋巴血管侵入淋巴血管侵入预后预后预后

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