诊断和管理牛奶过敏的区域差异
Fabian Hendricx1, Emma Robert1, Jaime A Ramirez-Mayans2
1Vrije Universiteit Brussel (VUB), UZ Brussel, KidZ Health Castle, Belgium.
Clinical and experimental pediatrics
|October 28, 2024
概括
全球专家在牛奶过敏 (CMA) 诊断和管理方面达成共识,同意配方选择,并拒绝将结肠作为唯一指标. 然而,大豆配方和益生菌使用的区域差异出现了,突出了需要本地化指南的需要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 过敏 免疫学 免疫学
- 临床营养学 临床营养学
背景情况:
- 对于诊断和管理牛奶过敏 (CMA) 已有确定的指导方针.
- 专家的共识对于完善诊断和管理策略至关重要.
研究的目的:
- 对墨西哥,中东和欧洲儿科胃肠病学,肝病学和营养学学会 (ESPGHAN) 的CMA诊断和管理陈述的专家投票结果进行比较.
- 确定关于牛奶过敏 (CMA) 的专家意见的区域差异.
主要方法:
- 三个不同的专家组匿名投票对10个关于CMA的相同陈述进行了投票.
- 达成一致被定义为9分中≥6分;不同意是<5.5分.
- 如果不到75%的参与者同意,声明将被拒绝.
主要成果:
- 在关键CMA方面达到了广泛的共识,包括拒绝婴儿结肠作为唯一的诊断标准.
- 对于轻度/中度CMA,优先选择大量化配方,以化大米作为替代品;基于氨基酸的配方适用于严重病例.
- 在大豆配方建议和益生菌/益生菌/共生菌在消除饮食中的价值中发现的差异,受地理,文化和经济的影响.
结论:
- 虽然所有声明都被接受,但在CMA管理方面仍然存在显著的区域差异.
- 关于大豆配方奶粉和辅助疗法的意见差异凸显了对特定区域指导方针的需求.
- 地理,文化,经济和配方可用性因素影响专家对牛奶过敏 (CMA) 的建议.
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