基于金属结合的纳米粒子作为先进的抗微生物层的协同抗微生物纳米纤维膜
Piumika Yapa1, Imalka Munaweera1, Manjula M Weerasekera2
1Department of Chemistry, Faculty of Applied Sciences, University of Sri Jayewardenepura Nugegoda 10250 Sri Lanka imalka@sjp.ac.lk laksiri@sjp.ac.lk piumikayapa@gmail.com +94 772943738.
RSC advances
|October 28, 2024
概括
这项研究开发了一种新型的抗微生物膜,在纤维素酸纳米纤维中使用金属合的二氧化纳米粒子. 由此产生的材料表现出广泛的抗菌活性和激素清除,提供了自我杀菌的解决方案.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术纳米技术
- 生物医学工程 生物医学工程
背景情况:
- 越来越多的公众对预防性医疗保健的重视,需要先进的抗菌材料.
- 现有的材料往往缺乏广泛的有效性,成本效益或生物降解性.
- 纤维素酸纳米纤维为开发功能性材料提供了一个多功能平台.
研究的目的:
- 开发一种创新的抗微生物膜材料,以提高健康和安全.
- 将金属合的纳米粒子 (Ag,Cu,Co) 纳入纤维素纳米纤维.
- 评估材料的自我杀菌,激素清除和抗菌性质.
主要方法:
- 通过电制造纤维素酸 (CA) 纳米纤维膜.
- 将金属化纳米颗粒 (Ag,Cu,Co) 纳入西拉诺网络.
- 使用PXRD,FTIR,Raman,SEM,TEM,TGA和拉伸测试进行全面的表征.
- 评估带隙能量,激素清除活性 (DPPH测定),以及对各种细菌和真菌菌株的抗菌疗效.
主要成果:
- 在CA纳米纤维中成功将金属合的化纳米颗粒纳入,通过表征技术证实了这一点.
- 制造膜表现出可见光活性,带隙能量低于3.00 eV.
- 三金属纳米混合体显示了最低的带隙能量 (2.84 eV),最高的激素清除活性 (91.77 ± 0.88%),以及对测试的微生物显著的抑制区.
- 已证明对*黄金葡萄球菌*,肺炎菌,MRSA,大肠杆菌,肺炎菌,假球菌,Trichophyton rubrum,Microsporum gypsium,Aspergillus niger和Candida albicans的有效性.
结论:
- 开发的自灭菌CA子是可行的,负担得起的,具有成本效益的,可生物降解的.
- 该材料具有广泛的抗菌疗效和双重物理/生物屏障特性.
- 这种创新的膜对于需要微生物控制的各种应用具有重大潜力.
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