哺乳可以保护母亲免受肥胖吗?
Süleyman Coşgun1, Derya Ünal2, Aysun Çalışkan Kartal3
1Internal Medicine, Gastroenterology, Kütahya University of Health Sciences, Kütahya, TUR.
Cureus
|October 28, 2024
概括
至少六个月的母乳养可以通过降低身体质量指数 (BMI),与非酒精性脂肪肝疾病 (NAFLD) 相关的因素来保护母亲的健康. 与较短的哺乳期相比,更长的哺乳期显示了BMI的显著差异.
科学领域:
- 内分泌学 在内分泌学.
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
背景情况:
- 改变生活方式有助于增加肝硬化 (脂肪肝疾病) 的发生率.
- 虽然经常无症状,但如果不加以管理,肝骨病会导致严重的并发病.
- 现有的文献提出了关于母乳养对抗肝硬化症的保护作用的相互矛盾的证据.
研究的目的:
- 为了研究母乳养时间,代谢健康和脂肪肝疾病之间的关联.
- 探索哺乳期,胰岛素抵抗和肝纤维化标志物之间的关系.
主要方法:
- 一项涉及135名至少怀孕过一次的女性 (20-40岁) 的横截面研究.
- 包括一个45名从未哺乳过的医疗保健工作人员的对照组.
- 收集的数据包括BMI,母乳养时间,胰岛素耐药性 (HOMA-IR),NAFLD纤维化得分和FIB-4得分.
主要成果:
- 在总母乳养时间和BMI,NAFLD纤维化得分,HOMA-IR或HbA1c之间没有发现显著的相关性.
- 在母乳养<6个月和>6个月的妇女之间观察到BMI的显著差异 (p=0.02).
- 体重指数显示与NAFLD (p=0.00) 和HOMA-IR (p=0.00) 有显著的关系;在对照组和母乳养组之间,FIB-4和NAFLD纤维化得分有显著差异.
结论:
- 为了母亲和婴儿的健康,建议保持至少六个月的哺乳期.
- 需要进一步的综合性研究来收集关于母乳养益处的长期数据.
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