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预防性雾化胺与利多卡因用于儿童桃体切除术后疼痛管理:一项比较研究
Manikandan Seetharamaraju1, Sridevi Mulimani1, Anusha Suntan1
1Anesthesiology, Shri B M Patil Medical College Hospital, Bijapur Lingayat District Educational Association (BLDE) (Deemed to be University), Vijayapura, IND.
Cureus
|October 28, 2024
概括
与利多卡因或盐水相比,预防性雾化胺显著降低了接受桃体切除术的儿童的救援止痛的需要. 这种有效的策略可以改善儿科患者的术后疼痛控制.
科学领域:
- 麻醉学 麻醉学
- 儿科手术 儿科手术
- 疼痛管理 疼痛管理
背景情况:
- 桃体切除术通常会导致严重的术后疼痛,目前的疼痛管理策略往往不令人满意.
- 在小儿桃体切除术后有效控制疼痛仍然是一个重大的临床挑战.
研究的目的:
- 为了比较先发性 nebulized ketamine 与先发性 nebulized lidocaine 和 nebulized 盐水在经过桃体切除术的儿童手术后疼痛的疗效.
主要方法:
- 一个潜在的随机临床试验,涉及105名儿科患者 (美国麻醉学会I和II) 接受桃体切除术.
- 患者被随机分为三个组:预防性雾化胺 (K组),利多卡因 (L组) 或盐水 (C组).
- 术后疼痛的评估是使用面部疼痛尺度修订 (FPS-R),镇静得分和在前六小时内救援止痛要求.
主要成果:
- 与利多卡因和盐水相比,预防性雾化胺显著降低了救援止痛的需要 (p<0.05).
- 只有14.3%的凯胺组患者需要救援止痛,而利多卡因组的85.7%和对照组的91.4%需要救援止痛.
- 雾化胺证明了术后疼痛和止痛药需求的显著减少.
结论:
- 预防性化胺是一种有效的策略,用于减少经过桃体切除术的儿童的术后疼痛.
- 与 nebulized lidocaine 相比,雾化胺在儿科桃体切除患者群体中提供了优越的疼痛控制.
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