皮肤冠状动脉干预后胃肠道出血:发生率,危险因素和结果
Ahmed Al-Hatmi1, Marwa Al-Habsi2, Malik Al-Ghafri2
1Internal Medicine Training Program, Oman Medical Specialty Board, Muscat, OMN.
Cureus
|October 28, 2024
概括
胃肠道出血 (GIB) 在皮肤冠状动脉干预 (PCI) 后一年内发生在3.4%的患者中. 高龄和某些疾病是PCI后GIB的关键风险因素.
科学领域:
- 心脏病学 心脏病学
- 胃肠病学 胃肠病学
- 临床医学 临床医学
背景情况:
- 穿皮冠状动脉干预 (PCI) 是冠状动脉疾病的标准治疗方法.
- PCI需要抗血小板治疗,增加胃肠道出血 (GIB) 的风险.
- 了解GIB发病率和PCI后的原因对于患者管理至关重要.
研究的目的:
- 在PCI之后的一年内确定GIB的发病率,原因和结果.
- 在接受PCI的患者中识别与GIB相关的风险因素.
- 在这个患者群体中为GIB提供预防策略的信息.
主要方法:
- 在苏丹卡布斯大学医院接受PCI的435名患者的回顾性分析 (2017年).
- 胃肠道出血 (GIB) 定义在心肌梗塞 (timi) 出血分数中使用血栓分析.
- 用于确定GIB显著风险因素的二进制物流回归 (p<0.05).
主要成果:
- 在PCI后一年内,GIB的发病率为3.4% (15名患者).
- 常见的表现包括黑色素 (53.3%) 和血 (20.0%);胃潰瘍疾病是主要原因 (40%).
- 严重的GIB风险因素包括晚年,慢性病,先前的胃潰瘍疾病和NSAID使用.
结论:
- 在PCI后观察到的GIB发病率与之前的研究一致.
- 在PCI前对出血的风险分层是必不可少的,特别是在高风险人群中.
- 建议考虑预防性胃保护,以减少PCI患者的GIB风险.
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