"我来了,因为我看到你关心我":招募老年黑人美国人进行基因组研究
Jodi M Winship1, Marissa Mackiewicz1, Muhammad Babar2,3
1Department of Gerontology, Virginia Center on Aging, Virginia Commonwealth University, Richmond, VA.
Ethnicity & disease
|October 28, 2024
概括
黑人老年人的基因组研究素养较低,影响了参与. 建立信任和证明个人相关性是吸引不同人群参与基因组研究的关键.
科学领域:
- 基因组学就是基因组学.
- 健康差异 在健康上的差异
- 精准医学是一门精准的医学.
背景情况:
- 基因组研究缺乏多样性,影响了对人类变异和精准医学公平性的理解.
- 黑人老年人在基因组研究中代表性不足,这限制了对他们的特定基因组资料的洞察力.
- 了解参与者的观点对于改善招聘和代表性至关重要.
研究的目的:
- 探索关于基因组研究的黑人老年人的知识,态度和信仰.
- 确定影响参与基因组研究的意愿因素.
- 了解招募黑人美国人进行基因组研究的障碍.
主要方法:
- 使用半结构面试对16名参与基因组研究的黑人老年人进行定性研究.
- 感应性主题分析来解释采访数据.
- 参与者的人口统计数据包括平均年龄为70岁,82%的人报告年收入<15,000美元.
主要成果:
- 基因组研究被参与者理解得很差,即使是那些有先前经验的人.
- 关于健康的文化信仰影响研究参与.
- 对卫生系统的不信任,源于历史因素,扩展到对研究的不信任.
- 建立关系,感知个人相关性和意义对于参与至关重要.
- 激励和便利是次要的明显的个人利益和研究相关性.
结论:
- 建立关系和提高研究素养对于吸引不同人群至关重要.
- 解决不信任和证明个人相关性对于招募黑人美国人至关重要.
- 需要新的战略来确保基因组研究中的公平代表性.
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