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Updated: Jun 9, 2025

Single-Molecule Imaging of EWS-FLI1 Condensates Assembling on DNA
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DNA的灵活性调节了转录因子与核体结合的转录因子

Luca Mariani1, Xiao Liu1,2, Kwangwoon Lee1,3

  • 1Division of Genetics, Department of Medicine; Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115.

bioRxiv : the preprint server for biology
|October 28, 2024
PubMed
概括

先驱转录因子启动染色体开放,但只结合少数点. 核子体内的DNA序列上下文,而不是因子本身,决定了这些关键的先驱因子结合的地方.

关键词:
在 ChIP-seqq.在DNA结合部位.灵活性 DNA 的灵活性.开拓者-seqqq 在这里.转录因子 转录因子高通量核细胞组结合试验.核细胞是核细胞的组成部分.开拓者就是开拓者.

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