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Updated: Jun 9, 2025

Quantifying Replication Stress in Ovarian Cancer Cells Using Single-Stranded DNA Immunofluorescence
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Published on: February 10, 2023

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TRIM24指导复制性应激反应通过染色体信号传递来维持ALT端粒

Daein Kim, Ragini Bhargava, Shih-Chun Wang

    bioRxiv : the preprint server for biology
    |October 28, 2024
    PubMed
    概括

    科学家们开发了BLOCK-ID来研究基因组复制压力. 他们发现TRIM24蛋白对于癌症中的端粒替代延长 (ALT) 至关重要,通过一种新的染色体信号通路协调端粒合成.

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