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Updated: Jun 9, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
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Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

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对共转录RNA折叠中间体进行序列结构探测

Courtney E Szyjka1, Skyler L Kelly1, Eric J Strobel1

  • 1Department of Biological Sciences, The University at Buffalo, Buffalo, NY 14260, USA.

bioRxiv : the preprint server for biology
|October 28, 2024
PubMed
概括

我们开发了一种新方法,TECprobe-LM,可以在转录过程中直接观察RNA折叠. 这种技术跟踪RNA结构的重排随着新核酸的添加,提供了更清晰的共转录RNA折叠路径的视图.

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