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Updated: Jun 9, 2025

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting
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酸化使SARS-CoV-2核体蛋白在两个膜相关的凝结态之间切换

Bruna Favetta1, Huan Wang2, Jasmine Cubuk3

  • 1Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.

bioRxiv : the preprint server for biology
|October 28, 2024
PubMed
概括

酸化改变了SARS-CoV-2核体蛋白 (N),改变了它与RNA和膜的相互作用. 这种分子开关影响病毒生命周期功能,并提供潜在的COVID-19治疗点.

关键词:
这就是SARS-CoV-2病毒.液-液相分离 (LLPS) 是一种液相分离技术.材料属性 材料的属性膜相互作用的相互作用.酸化的方法是:光化.蛋白质-RNA相互作用

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