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Updated: Jun 9, 2025

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
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A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1

Published on: March 18, 2017

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DDX41溶解G-四重复合体,以保持红色球体基因组完整性,并防止cGAS介导的细胞死亡

Honghao Bi, Kehan Ren, Pan Wang

    bioRxiv : the preprint server for biology
    |October 28, 2024
    PubMed
    概括

    有害的DDX41变体会导致骨髓瘤瘤的发生. 这项研究揭示了DDX41溶解G-四重复合体,保持红色球体基因组的稳定性,并抑制cGAS-STING通路,这对于预防这些血液疾病至关重要.

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