CD8+T

Joseph Longo1, Lisa M DeCamp1, Brandon M Oswald1

  • 1Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.

概括

葡萄糖通过使糖脂 (GSL) 合成,促进T细胞扩张,这对它们的功能至关重要. 这条通路对于CD8+T细胞细胞毒性活动和瘤控制至关重要,独立于能量生产.

相关概念视频

T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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