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Updated: Jun 9, 2025

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氨基酸替代品的适应性分配法

Mengyi Sun1, Arlin Stoltzfus2,3, David M McCandlish1

  • 1Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.

bioRxiv : the preprint server for biology
|October 28, 2024
PubMed
概括

预测蛋白质中的氨基酸替代具有挑战性. 这项研究揭示了体能效应的最大分布,根据实验数据,准确地模拟分子进化模式,并帮助蛋白质工程.

关键词:
氨基酸是氨基酸中的一种.深度突变扫描 (deep mutational scanning) 是一种对突变进行深度扫描的方法.史诗主义就是一种史诗主义.分子进化分子演变.蛋白质设计 蛋白质设计

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