2013年至2024年的奥利塞里丁 (TRV130) 全球趋势研究:一个图书识别和知识图分析
Cong Wang1, Lidan Liu1, Xue Bai2
1Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People's Republic of China.
Drug design, development and therapy
|October 28, 2024
概括
奥利塞里丁表明作为一种更安全的阿片类药物替代品来治疗疼痛,研究重点是其机制和临床疗效. 图书统计分析揭示了这一新型止痛药的关键趋势和未来研究方向.
科学领域:
- 药理学和药物化学 药理学和药物化学
- 疼痛管理研究 疼痛管理研究
- 图书统计分析 图书统计分析
背景情况:
- 阿片类药物带来重大风险,包括不良影响和滥用潜力,推动寻找更安全的替代品.
- 与传统阿片类药物相比,奥利塞里丁正在成为一个有前途的候选药物,因为与传统阿片类药物相比,呼吸系统抑郁和胃肠道问题的风险可能更低.
- 了解奥利塞里丁的研究环境对于推进疼痛管理疗法至关重要.
研究的目的:
- 通过参考文献分析,探索oliceridine研究的知识结构.
- 确定临床应用,特别是在急性疼痛管理中.
- 突出可能降低成风险的机制,指导未来的研究.
主要方法:
- 对2013年至2024年发表的159篇文章进行了图书统计分析.
- 利用了科学网络核心集合数据库.
- 使用Citespace,Vosviewer和Bibliometrix软件进行数据可视化和分析.
主要成果:
- 研究集中在奥利塞里丁的分子/药理机制和临床疗效/安全.
- 美国在研究成果方面处于领先地位.
- 关键的研究热点包括蛋白质偏差连接体和奥利塞里丁本身,未来的重点预计是偏差信号机制和药物设计.
结论:
- 图书统计分析提供了关于奥利塞里丁研究当前和新兴趋势的有价值的见解.
- 这些发现可以指导未来关于奥利塞里丁安全性和有效性的研究.
- 奥利塞里丁的日益关注和临床应用支持进一步的开发和试验.
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