计算机控制的混合振荡式风扇的设计和实施
Andrea F Cruz1, Jacob Herrmann2, Bakir Hajdarevic3
1Department of Anesthesia, University of Iowa, 200 Hawkins Dr, Iowa City, IA 52242.
Journal of medical devices
|October 28, 2024
概括
开发了一种新的混合振荡呼吸机,以改善肺功能和气体交换. 该设备支持多频振荡式通风 (MFOV) 进行潜在的不那么有害的机械通风.
科学领域:
- 生物医学工程 生物医学工程
- 呼吸系统生理学 呼吸系统生理学
- 机械通风机械通风机械通风
背景情况:
- 在异质肺部,可以使用多频振荡通风 (MFOV) 改善肺功能和气体交换.
- 传统的高频振荡式通风 (HFOV) 使用单一的频率,限制了潜在的好处.
- 存在对能够使用MFOV和其他通风模式的先进通风器的需求.
研究的目的:
- 设计和测试计算机控制的混合振荡式通风机.
- 为了实现多频振荡通风 (MFOV),高频振荡通风 (HFOV),常规机械通风 (CMV) 和振荡计.
- 评估设备在维持气体交换方面的性能和有效性.
主要方法:
- 开发了一种计算机控制的混合振荡式呼吸机,配备了一种代光谱反控制器.
- 在音量控制模式下对商用通风机进行了设备性能测试.
- 在机械试验肺中验证的振荡模式 (420 Hz,530 cmH2O平均气道压力).
- 在猪型急性肺损伤模型上进行了概念验证实验.
主要成果:
- 该设备在音量控制模式下满足商用通风机的性能标准.
- 振荡式通风模式在机械试验肺中满足了设计规格.
- 呼吸机成功地维持了猪急性肺损伤模型中的适当气体交换.
- 该设备展示了产生各种通风波形的能力.
结论:
- 一个新的混合振荡式呼吸机成功设计和测试.
- 该设备可以产生各种常规和振荡式通风波形.
- 这项技术有可能改善气体交换并提供不那么有害的通风.
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