青春期前的肥胖对停止信号任务中的抑制控制的影响:功能性EEG网络研究
Yuqin Li1, Qian Yang1, Yuxin Liu1
1The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and TechnologyUniversity of Electronic Science and Technology of China Chengdu 611731 China.
IEEE open journal of engineering in medicine and biology
|October 28, 2024
概括
儿童肥胖与大脑网络发育的改变有关,影响抑制控制和认知表现. 肥胖儿童与不肥胖的同龄人相比,显示出不同的大脑网络模式.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 儿科健康 儿科健康
背景情况:
- 儿童肥胖是一个日益严重的公共卫生问题.
- 关于儿童肥胖,认知功能和大脑网络变化之间的联系的理解有限.
- 停止信号任务对于评估抑制控制和冲突监测至关重要.
研究的目的:
- 研究儿童肥胖和功能性大脑网络之间的关系.
- 在肥胖和非肥胖的青少年中分析停止信号任务期间的大脑网络属性.
- 探索身体质量指数 (BMI) 和大脑网络特征之间的相关性.
主要方法:
- 利用公开可用的数据集进行分析.
- 在停止信号任务期间检查功能性脑网络连接和属性.
- 在肥胖和非肥胖的青少年前群体之间比较网络特征.
- 评估了网络指标和BMI之间的相关性.
主要成果:
- 肥胖和不肥胖的儿童在高需求条件下 ("不去"与"去") 显示了网络连接的增加.
- 肥胖的青春期前期显示显著增强的前额-双肩,前额-头和前额-部网络链接.
- 在这两种任务条件下,在肥胖儿童中观察到网络效率提高.
- 网络属性与BMI有显著的相关性,可以预测BMI得分.
结论:
- 儿童肥胖与前额基于大脑网络的非典型发展有关.
- 这些网络变化会影响肥胖儿童的抑制控制和认知表现.
- 肥胖的后果超越了身体健康,影响神经发育和功能.
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