在新诊断的多发性硬化症中自我报告的饮食回忆的可行性和评估:一个准实验性的试点研究
Solange M Saxby1,2, Mary A Ehlinger1, Lisa Brooks1
1Department of Internal Medicine, University of Iowa, Iowa City, IA, United States.
Frontiers in nutrition
|October 28, 2024
概括
修改后的旧石器时代饮食,作为健康行为干预的一部分,可能会减少多发性硬化症 (MS) 患者的添加糖摄入量. 然而,它也存在营养不足的风险,强调在MS治疗中需要仔细的饮食规划.
科学领域:
- 营养科学 营养科学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 许多患有临床隔离综合征 (CIS) 或复发性复发性多发性硬化症 (RRMS) 的人因成本或副作用而拒绝疾病修饰疗法 (DMT).
- 饮食修改,特别是修改的古石器时代消除饮食,正在被探索为MS症状管理的替代疗法.
- 潜在的营养不足是限制性消除饮食的一个问题.
研究的目的:
- 评估在多发性硬化症 (MS) 患者群体中使用自动自主24小时 (ASA24) 饮食评估工具的可行性.
- 与标准护理 (SOC) 相比,评估MS患者的饮食摄入量和营养充足度,接受多式联络健康行为 (HB) 干预.
主要方法:
- 一个为期12个月的准实验性试验比较了HB组 (饮食修改,运动,呼吸) 与标准护理 (SOC) 组.
- 通过ASA24工具评估饮食摄入量,使用三个24小时的回忆.
- 微量营养素摄入量根据估计平均需求 (EAR) 进行了评估.
主要成果:
- ASA24工具被证明是可行的,在两组中都超过了80%的坚持.
- 乙型肝炎组显示,谷物和添加糖的摄入量减少,肉摄入量增加.
- 两组人都出现了显著的营养不足,特别是维生素D和维生素E以及. 在SOC小组中,存在更广泛的不足.
结论:
- 在多式干预中遵守修改后的旧石器时代饮食可能会减少添加糖的摄入量,但可能会增加严重营养不足的风险.
- ASA24工具是对MS患者饮食评估的一种可行的方法.
- 对于那些采取限制性饮食的MS患者来说,仔细的营养监测是必不可少的.
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