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角膜稀薄和融化的进展在原交叉连接后用于角质

Shreesha Kumar Kodavoor¹, Suvarna Chaji Sugali¹, Gopinathan Selvaraju²

¹The Eye Foundation, Coimbatore, India.

Romanian journal of ophthalmology

|October 28, 2024

概括

在原交叉链接 (CXL) 后角膜稀薄是罕见但严重的. 及时治疗对于预防患有这种CXL并发症的患者的视力损失至关重要.

科学领域:

眼科医生眼科眼科
角膜外科手术角膜外科手术
眼睛表面疾病眼睛表面疾病

背景情况:

视角稀疏后原交叉链接 (CXL) 是一种不常见但可能危及视力的并发症.
了解它的病因学,临床过程和管理对于患者的结果至关重要.

研究的目的:

调查CXL后角膜变薄的原因,临床特征,治疗方法和预后.
为了确定这种罕见的并发症的风险因素和最佳管理策略.

主要方法:

在CXL后角膜变薄的患者进行了回顾性观察性研究.
收集的数据包括手术前的细节,临床表现,调查结果,管理和后续情况.
在南印度的一家三级眼科医院进行的研究 (2011-2017).

主要成果:

12名患者 (8名女性,4名男性) 在CXL后5-12年出现角膜变薄.
女性患者的危险因素包括怀孕,哺乳期,试管婴儿和糖尿病和甲状腺功能障碍等并发症.
临床表现各不相同,包括下垂体,穿孔和上皮缺陷;最薄的角膜厚度在212-351微米之间.
治疗包括角质整形 (PKP/DALK),蓝酸粘合剂或保守的管理;4名患者没有进展.

结论:

在CXL之后的角膜稀疏是罕见的,但可能是严重的,并迅速进展.
及时和适当的干预对于减轻视觉发病率至关重要.

关键词:

AS-OCT = 前部眼部连贯性断层扫描.BCVA = 最好的校正视力敏度 CF = 计数数量的数字.CXL = 原的交叉链接 DALK = 深前叶膜角质塑造.DM = 糖尿病类糖尿病电子记录媒体 (EMR) = 电子记录媒体.试管婴儿=体外受精在体外受精.KC = 角质球 = 角质球 MMP = 矩阵金属蛋白酶.PKP = 穿透式角质塑造 TCT = 角膜最薄的厚度原蛋白交叉链接的交叉链接形 (keratoconus) 是一种形.在CXL后,角膜变薄.

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