甲状腺结节与AUS细胞病理学的恶性瘤的患病率:一个回顾性横截面研究
Abdullah M Alshalaan1, Waleed A D Elzain1, Jaber Alfaifi1
1Department of Internal Medicine, Armed Forces Hospitals Southern Region, Khamis Mushait, Kingdom of Saudi Arabia.
Journal of family medicine and primary care
|October 28, 2024
概括
在沙特阿拉伯,甲状腺结节与未确定的意义的缺血症 (AUS) 显示出显著的恶性瘤率. 超声波的特征,如回声性和化,有助于预测恶性瘤,支持细针吸收细胞学 (FNAC) 的有效性.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 细胞病理学 细胞病理学
背景情况:
- 贝塞斯达甲状腺细胞病理报告系统 (TBSRTC) 将不确定的甲状腺结节归类为III类 (AUS).
- 意义不明的非典型性 (AUS) 代表甲状腺结节的发现,既不是绝对良性的,也不是恶性的.
- 确定与AUS相关的恶性瘤风险对于患者管理至关重要.
研究的目的:
- 确定诊断为AUS的患者甲状腺恶性瘤的发生率.
- 评估细针吸收细胞学 (FNAC) 和术后组织病理学之间的诊断相关性.
- 为了调查超声波特征与AUS甲状腺结节中的恶性瘤的关联.
主要方法:
- 508名被诊断患有AUS甲状腺结节的患者的回顾性图表审查.
- 细针吸收细胞学 (FNAC) 结果和随后的病原学分析.
- 统计分析以评估细胞病理学,组织病理学和超声波特征 (回声性,化) 之间的相关性.
主要成果:
- 在患有AUS甲状腺结节的患者中观察到37.2%的恶性瘤率.
- 乳头癌是最常见的恶性瘤 (80.4%的恶性病例).
- 发现FNAC和组织病理学 (P <0.05),回声性和化 (P = 0.003和P = 0.001分别) 与恶性瘤之间存在显著的相关性.
结论:
- 在沙特阿拉伯,甲状腺结节与AUS细胞病理学具有显著的恶性瘤率.
- FNAC显示出诊断价值,得到了强烈的与术后组织病理学相关性的支持.
- 结节的回声性和化是AUS病例中恶性瘤的潜在预测因素.
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