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伊朗东南部的Leishmania Tropica引起的犬类莱什曼病:一个案例系列研究

Baharak Akhtardanesh¹, Soheil Sadr², Javad Khedri²

¹Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran. akhtardanesh@uk.ac.ir.

Scientific reports

|October 28, 2024

概括

这项研究发现,伊朗东南部的狗中Leishmania tropica感染的数量显著增加,这表明狗可能在将这种疾病传播给人类方面发挥更大的作用. 在特有地区重新评估了犬类莱什曼病的流行率.

科学领域:

兽医医学兽医医学兽医医学
传染性疾病传染性疾病
寄生虫学的寄生虫学

背景情况:

狗是Leishmania infantum的主要存储库,但Leishmania tropica也可以感染狗并传播给人类.
狗病 (CanL) 在伊朗东南部非常普遍,兽医经常看到有症状的病例.

研究的目的:

评估在伊朗扎博尔和克尔曼拥有皮肤病变的狗中CanL的患病率.
为了确定负责该地区犬类皮肤莱什曼病的莱什曼尼亚物种.

主要方法:

从2017年12月到2022年11月,对500只皮肤病变的狗进行了一系列病例研究.
印象涂抹,血清学 (ELISA) 和分子 (嵌套PCR) 方法用于诊断和物种识别.

主要成果:

显微镜检查检测到Leishman体在7.2%的狗.
在12只狗 (Zabol: 2, Kerman: 8) 和Leishmania infantum在26只狗 (Zabol: 10, Kerman: 16) 中发现了热带犬病.
分子分析在27.7%的阳性病例中证实了L. tropica,这与以前的研究相比显著增加.

结论:

这项研究强调了伊朗东南部狗中热带犬菌的严重流行情况.
这些发现表明,狗作为L. tropica的储存库的作用应该在特有地区重新评估.

关键词:

莱什马尼亚热带的热带皮肤上的莱什曼病.狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗伊朗伊朗伊朗伊朗

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