体重调整的腰指数与高血压老年人中发生的中风之间的关联:一项队列研究
Junli Hu1, Xintian Cai1, Shuaiwei Song1
1Hypertension Center of People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region, Hypertension Research Laboratory, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, Urumqi, China.
Scientific reports
|October 28, 2024
概括
体重调整的腰部指数 (WWI) 与高血压的老年人中风风险增加有关. 较高的WWI值与发展中风的可能性更高相关.
科学领域:
- 心血管医学 心血管医学
- 老年病的医生 老年病的医生
- 流行病学 流行病学
背景情况:
- 高血压是老年人中风的主要危险因素.
- 体重调整腰部指数 (WWI) 是中心肥胖的一个新兴指标.
- 第一次世界大战与高血压老年人中风险之间的关联仍然不清楚.
研究的目的:
- 调查基线体重调整腰部指数 (WWI) 与新发性中风风险之间的关系.
- 确定WWI是否可以作为老年高血压患者的风险分层工具.
主要方法:
- 一项队列研究,涉及4962名高血压患者,年龄在60岁以上,以前没有中风.
- 考克斯回归模型和受限立方线被用于分析第一次世界大战和中风发病率,平均随访时间为3.2年.
- 进行了子组分析和相互作用测试以评估异质性.
主要成果:
- 第一次世界大战的基线升高显著与中风风险增加有关.
- 卒中风险比率随着第一次世界大战四分位数的上升而逐渐增加.
- 与最低四分位数相比,第一次世界大战四分位数最高的四分位数显示中风风险增加1.87倍 (HR 1.87,95% CI 1.44-2.42).
结论:
- 较高的体重调整腰部指数是老年高血压患者中风风险的独立预测指标.
- WWI可能是一个有价值的工具,用于识别患中风风险较高的人.
- 需要进一步的研究来证实这些发现,并探索潜在的因果机制.
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