60岁或以上的韩国老年人疼痛和认知功能:一项追溯纵向研究
Yun-A Kim1, Yoon Jeong Cho1, Sang Gyu Kwak2
1Department of Family Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.
Medicine
|October 28, 2024
概括
疼痛会对老年人的认知功能产生负面影响. 该研究发现,疼痛,特别是高冲击性疼痛,在60岁及以上的个人中显著增加了认知障碍和疑似痴呆症的风险.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 慢性疼痛在老年人中很普遍,可能会影响认知健康.
- 认知能力下降,包括痴呆症,是老年人群日益严重的公共卫生问题.
- 了解疼痛和认知之间的相互作用对于开发有效的干预措施至关重要.
研究的目的:
- 调查60岁及以上的韩国成年人疼痛与认知衰退之间的关联.
- 为了确定疼痛对认知功能的影响是否根据疼痛严重程度不同 (低影响与高影响).
- 分析纵向数据以了解随时间的关系.
主要方法:
- 利用来自韩国老龄化长度研究的3,287名韩国成年人 (≥60岁) 的数据.
- 评估疼痛的存在和干扰,使用自我管理的问卷,将参与者分为没有,低影响和高影响的疼痛组.
- 使用韩国迷你精神状态检查 (K-MMSE) 评估认知功能,将得分分类为正常,认知障碍和疑似痴呆类别.
- 采用回归分析来调整混因素,并对疼痛干扰进行子组分析.
主要成果:
- 在疼痛和K-MMSE得分之间发现了显著的负相关性 (P < .001).
- 疼痛在八个波段的认知分数中始终显示出负相关性,即使在调整混因子 (β = -1.170) 之后也是如此.
- 疼痛的存在使疑似痴呆的几率增加了1.56倍,认知障碍的几率增加了1.36倍.
- 与低影响性疼痛相比,高影响性疼痛将疑似痴呆的几率提高了2.12倍,认知障碍的几率提高了1.47倍.
结论:
- 疼痛与较差的认知功能和较高的认知障碍和疑似痴呆症的风险在韩国老年人中显著相关.
- 疼痛干扰的严重程度与认知能力下降的风险直接相关,高影响性疼痛构成更大的威胁.
- 研究结果强调了疼痛管理在老年人群中保持认知健康的重要性.
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