胰腺的SMARCB1缺乏的恶性瘤具有异质形态,不能被分类为现有的组织类型
Yusuke Kouchi1, Nozomu Sakai2, Sakurako Harada-Kagitani1,3
1Department of Molecular Pathology, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba, Japan.
Pathology international
|October 28, 2024
概括
一种罕见的胰腺瘤,具有透明和上皮细胞,具有SMARCB1损失,转移到肝脏. 这种遗传缺陷可能会在这个具有挑战性的病例中驱动瘤发生.
科学领域:
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
- 病理学 病理学 病理学
背景情况:
- 对胰腺尾部瘤进行远端胰腺切除术.
- 超慢性肝转移需要进一步的手术干预.
- 瘤异质性带来了诊断方面的挑战.
相关概念视频
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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
The Ras Gene
The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
Ras is a superfamily...
Ras is a superfamily...


