脊髓损伤和整体和特定类型心血管疾病的风险:一个元分析
ShengZhong Luo1,2,3, Tianlong Wu1,2,3, Xigao Cheng1,2,3
1Department of Orthopaedics, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
PloS one
|October 28, 2024
概括
脊髓损伤 (SCI) 患者面临显著更高的心血管疾病 (CVD) 风险,包括心脏病发作,心房动,心力衰竭和中风. 对这一群体来说,提高意识和主动管理至关重要.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 对脊髓损伤 (SCI) 患者来说是一个日益严重的健康问题.
- 了解SCI人群中心血管疾病的特定风险对于有效的医疗保健管理至关重要.
研究的目的:
- 进行元分析,探讨SCI与整体心血管疾病和特定心血管事件风险之间的关联.
- 与对照人群相比,在SCI患者中量化各种心血管结果的风险增加.
主要方法:
- 通过PubMed,Embase和Cochrane图书馆的数据进行了系统的元分析,截至2024年4月17日.
- 包括的观察性研究使用纽卡斯尔-太华和AHRQ尺度评估了偏差风险.
- 来自9项涉及超过220万个人的研究 (包括193,045名SCI患者) 的数据使用随机效应模型进行了汇总.
主要成果:
- SCI患者的整体心血管疾病风险增加了1.56倍.
- 观察到心肌梗塞 (1.58倍),心房动 (1.52倍),心力衰竭 (1.64倍) 和中风 (2.38倍) 的风险增加.
- 患有SCI和并发症的人患心血管疾病风险增加了1.48倍,而没有并发症的人患心血管疾病风险增加了2.10倍.
结论:
- 与一般人群相比,SCI患者的心血管疾病总体风险明显高于一般人群.
- 特定的心血管事件,包括心肌梗塞,心房动,心力衰竭和中风,在SCI患者中更为普遍.
- 医疗保健提供者应加强对脊髓损伤患者心血管疾病风险的警.
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