医学获取计划:患者认为什么 - - 澳大利亚转移性乳腺癌中患者报告的利博西基利布结果研究
Natasha Yap1, Vanessa Wong2,3, Catherine Morton2
1Department of General Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Internal medicine journal
|October 28, 2024
概括
转移性乳腺癌患者的患者获取计划 (PAP) 显示利,但意识有限. 需要改善教育和同意才能获得更好的患者结果和坚持.
科学领域:
- 在瘤学瘤学.
- 药物经济学 药物经济学
- 患者报告的结果
背景情况:
- 转移性乳腺癌 (MBC) 的治疗往往涉及高成本的药物.
- 药物获取计划 (MAP) 促进患者获得未经资助的药物.
- 了解MAP中的患者体验对于优化支持至关重要.
研究的目的:
- 评估澳大利亚MBC患者接受ribociclib的MAP患者的患者报告结果 (PROs).
- 确定与MAP招生相关的挑战和好处.
- 为未来患者援助计划的发展提供信息.
主要方法:
- 来自MBC患者的PRO的前性评估,这些患者接受了在MAP中注册的 ribociclib.
- 收集关于患者意识,感知益处和坚持的数据.
- 将PRO数据与现实世界注册表数据集成.
主要成果:
- 一个重要的发现是,患者对MAP招生流程的认识有限.
- 患者对获得非资助的 ribociclib.lib 的机会表示高度的感激.
- 提高药物坚持被参与者认为是关键的好处.
结论:
- 改善患者教育和同意流程对于MAP入学至关重要.
- MAP为MBC患者提供了显著的价值,特别是在药物获取和服药方面.
- 结合PRO和注册表数据,为MAP评估和改进提供了一个强大的框架.
相关概念视频
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Treatment Resistant Cancers
3.3K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K
Nursing Ethical Principles II
924
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
924


