相关实验视频

Updated: Jun 9, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

系统性免疫炎症指数与牛皮,牛皮并发症和全因死亡率之间的关联:基于NHANESES的研究

Yang Zhao¹, Yan Ping Bai², Lin Feng Li¹

¹Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Immunity, inflammation and disease

|October 28, 2024

概括

系统性免疫炎症指数 (SII) 与牛皮的更高患病率有关. 在牛皮患者中,SII升高与代谢综合征和死亡风险增加相关.

科学领域:

免疫学免疫学免疫学
皮肤病学皮肤病学
流行病学流行病学

背景情况:

系统性免疫炎症指数 (SII) 和牛皮之间的关系,包括其并发症和预后,仍然不清楚.
调查这种关联可以提供有关牛皮所涉及的炎症途径及其系统影响的见解.

研究的目的:

调查SII和牛皮的流行率之间的相关性.
检查SII和牛皮并发症之间的关联,特别是代谢综合征 (MetS).
评估患有牛皮的个体中SII和全因死亡率之间的关系.

主要方法:

分析了来自多个国家健康和营养检查调查 (NHANES) 周期 (2003-2014) 的21,431名参与者的数据.
使用加权的多变量逻辑回归模型来分析SII与牛皮/并发症之间的关联.
使用权重的COX回归来确定所有原因死亡的危险比率,随访数据延长至2019年12月31日.

主要成果:

在完全调整的模型中,在SII和牛皮发病率 (OR=1.20,p=0.01) 之间发现了积极的关联.
在牛皮患者中,SII与代谢综合征 (OR=1.68,p=0.004) 和全因死亡率 (HR=1.48,p=0.01) 有显著的关联.
这些关联在各种敏感性和子组分析中保持一致,包括当SII被分类分析时.

结论:

这项研究表明,较高的SII水平与牛皮的患病率之间存在积极联系.
牛皮患者的SII升高与更高的代谢综合征可能性和增加全因死亡风险有关.

关键词:

尼汉斯 (NHANES) 是一个名人.所有原因的死亡率.代谢综合征代谢综合征牛皮是一种牛皮.系统性免疫炎症指数

更多相关视频

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma

Published on: September 20, 2024

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

相关概念视频

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...

Psychoneuroimmunology: Diabetes and Cancer

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...

Inflammation

Inflammation

Factors Affecting the Risk of Infection

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...