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Updated: Jun 9, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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铜催化 γ-C ((sp3) -H 乳酸化和免疫乳酸化

Tao Sheng1, Zhe Zhuang1, Zhihan Zhao1

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.

Angewandte Chemie (International ed. in English)
|October 28, 2024
PubMed
概括

这项研究引入了一种新的铜催化方法,用于从托西尔保护的胺中合成g-lactams和g-iminolactones. 反应提供可切换的选择性和获取多样化,生物相关的化学结构.

关键词:
碳酸胺是碳酸胺的一种.铜铜 铜铜的铜.γ-iminolactonization 形成的 乳酸体 形成的 乳酸体γ - 乳糖化

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