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Updated: Jun 9, 2025

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外体miR-129-2-3p在PM2.5加重喘中促进呼吸道上皮层屏障的破坏

Caihong Wang1, Zeyu Niu2, Yan Zhang2

  • 1Department of Environmental Health, School of Public Health, Shanxi Medical University, China; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, China; Center for Ecological Public Health Security of Yellow River Basin, Shanxi Medical University, China; MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, China.

Journal of environmental management
|October 28, 2024
PubMed
概括

颗粒物2.5 (PM2.5) 暴露会通过破坏呼吸道屏障使喘恶化. 外体的miR-129-2-3p,由PM2.5升高,通过TIAM1/RAC1/PAK1通路破坏这些屏障,表明治疗点.

关键词:
呼吸道上皮质屏障 呼吸道上皮质屏障喘 喘 是一种异构体是什么? 异构体是什么? 外构体是什么?在PM中{2.5)在 miR-129-2-3p 中使用.

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