急性呼吸困扰综合征是什么
Katherine D Wick1, Lorraine B Ware2, Michael A Matthay3,4
1Division of Pulmonary, Critical Care, and Sleep Medicine, University of Minnesota, Minneapolis, MN, USA wick0411@umn.edu.
概括
对于急性呼吸困扰综合征 (ARDS) 的理解有所进化,新的定义和管理准则改善了生存率. 本综述涵盖了ARDS流行病学,病理生理学和重症监护干预措施,以改善患者的治疗结果.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 自1967年初次描述以来,对急性呼吸困扰综合征 (ARDS) 的理解已经发展.
- 基础科学和临床试验的进步已经阐明了ARDS病理生理学,并改善了死亡率.
- 综合性重症监护干预一直是管理ARDS的核心.
研究的目的:
- 审查目前对ARDS流行病学,病理生理学和管理的理解.
- 突出提出的ARDS的新全球定义.
- 为ARDS提供更新的管理指南.
主要方法:
- 关于ARDS流行病学,病理生理学和管理的文献综述.
- 综合目前关于重症监护干预措施的证据.
- 包括最近更新的ARDS定义和指导方针.
主要成果:
- 对ARDS的理解有了显著的进步,从而改善了患者的治疗结果.
- 建议对ARDS制定一个新的全球定义.
- 更新的管理指南强调了既有干预措施,如低潮量通风,易感定位和保守的流体策略.
结论:
- 目前的ARDS管理,以更新的定义和基于证据的干预措施为指导,降低了死亡率.
- 对ARDS病理生理学和新疗法的持续研究至关重要.
- 实施推的指导方针和未来的研究重点对于推进ARDS护理至关重要.
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