对比A模式超声波和计算机断层扫描来评估与癌症相关的肉症:一个横截面研究
Iasmin M Sousa1, Jarson P da Costa Pereira2, Rodrigo A B Rüegg1
1Postgraduate Program in Health Sciences, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil.
概括
A模式超声波 (美国) 显示,通过测量肌肉厚度来诊断癌症患者的肉症具有前途. 结合双肩和大腿的测量可以提高准确性,提供一个可行的床边工具.
科学领域:
- 医疗成像医学成像
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
背景情况:
- A模式超声波 (US) 是一种潜在的,但尚未探索的,用于直接测量癌症患者的肌肉厚度的方法.
- 评估肌肉质量对于癌症患者的管理和皮症的诊断至关重要.
研究的目的:
- 评估A模式US的可行性,以评估癌症患者的肌肉厚度.
- 将A模式的美国测量与计算机断层扫描 (CT) 衍生的肌肉横截面积 (CSA) 进行比较.
- 评估A模式US对萨尔科佩尼亚的诊断能力.
主要方法:
- 对120名住院癌症患者的横截面分析.
- 来自CT扫描的肌肉CSA;双肌肉厚度 (BMT) 和大腿肌肉厚度 (TMT) 通过A模式US测量.
- 萨科佩尼亚是由低肌肉质量 (CT或美国衍生) 加上低握力 (HGS) 定义的.
主要成果:
- 肌厚度 (TMT) 和联合的BMT+TMT测量与肌肉CSA有显著的相关性,解释了35%的变化.
- 单独和与 BMT 结合使用的 TMT,在男性中对萨尔科佩尼亚诊断的准确度最高 (AUC > 0.70).
- 使用联合BMT+TMT诊断的肉类瘤有最高频率 (34%) 和与CT衍生的肉类瘤有中等一致性 (κ=0.48).
结论:
- A模式US是一种潜在的可行的工具,用于癌症患者的床边肉症诊断.
- 结合BMT和TMT测量,提高了A模式US在萨尔科佩尼亚诊断中的临床意义.
- 对于A模式US的准确性进行进一步的改进是必要的,以获得广泛的临床采用.
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