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Updated: Jun 9, 2025

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阿西米尼布的临床药理学:一篇评论

Matthias Hoch1, Felix Huth2, Paul William Manley2

  • 1Novartis Biomedical Research, Fabrikstrasse 2, 4056, Basel, Switzerland. Matthias.hoch@novartis.com.

Clinical pharmacokinetics
|October 29, 2024
PubMed
概括

阿西米尼布是慢性髓性白血病的全抑制剂,显示可预测的药理动力学 (PK),不受患者因素的影响. 对于T315I突变患者,需要更高的暴露,没有与暴露水平相关的重大安全问题.

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