身体形状指数和动脉硬度之间的关联:EVasCu研究和元分析的结果
Alicia Saz-Lara1, Iván Cavero-Redondo2,3, Nerea Moreno-Herráiz1
1CarVasCare Research Group, Facultad de Enfermería de Cuenca, Universidad de Castilla-La Mancha, Cuenca, Spain.
International journal of obesity (2005)
|October 29, 2024
概括
身体形状指数 (ABSI) 与健康个体和一般人群的动脉硬性有关. 较高的ABSI表明中心,外周和全身动脉硬的风险增加.
科学领域:
- 心血管健康 心血管健康
- 生物识别信息 生物识别信息
- 公共卫生 公共卫生
背景情况:
- 动脉硬是心血管健康的一个关键指标.
- 身体形状指数 (ABSI) 是一种新型的人类测量方法,反映了身体脂肪的分布.
- 了解ABSI和动脉硬之间的关系对于风险评估至关重要.
研究的目的:
- 从EVasCu研究中分析身体形状指数 (ABSI) 与健康受试者的动脉硬之间的关联.
- 进行元分析,比较ABSI与一般人群中中心,外周和全身动脉硬之间的关联.
主要方法:
- 这项EVasCu研究包括390名健康受试者.
- 使用腰围,BMI和身高来计算ABSI.
- 使用大动脉脉冲波速 (a-PWv) 和心血管指数 (CAVI) 来评估动脉硬度.
- 进行了先前研究的元分析,包括EVasCu数据,以确定聚合的相关系数和赔率比率 (ORs).
主要成果:
- 在EVasCu研究中,在ABSI和a-PWv (r=0.458) 和CAVI (r=0.408) 之间发现了显著的正相关性.
- 分析揭示了ABSI与中心 (r=0.22),外围 (r=0.21) 和全身 (r=0.28) 动脉硬性的聚合相关系数.
- 聚合的OR显示风险增加:中心 (OR=2.12),外围 (OR=2.21),和系统 (OR=2.99) 动脉硬度每单位增加的ABSI.
结论:
- 在健康个体和并发症患者中,ABSI和动脉硬之间存在积极的关联.
- 每个单位的ABSI增加都会显著增加中枢,外围和全身动脉硬的风险.
- 需要进一步的研究来充分阐明这种关系.
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