高流量鼻氧疗法与老年慢性阻塞性肺病患者的非侵入性通风:一个非劣质的随机对照试验协议
Xinyuan Yang1, Jiangli Cheng1, Zhen Wang1
1Department of Respiratory Care, West China Hospital of Sichuan University, Guoxue Alley 37#, Wuhou District, Chengdu, 610041, Sichuan, China.
BMC pulmonary medicine
|October 29, 2024
概括
高流量鼻腔管 (HFNC) 可能是非侵入性通风 (NIV) 的安全和有效替代品,用于长期阻塞性肺病 (COPD) 的老年患者. 这项随机对照试验将比较HFNC和NIV之间的再灌输率和临床结果.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 关键的护理关键的护理
- 老年病的医生 老年病的医生
背景情况:
- 非侵入性通风 (NIV) 是用于输管慢性阻塞性肺病 (COPD) 患者的标准,但会导致不良事件,特别是在老年人中.
- 高流量鼻腔管 (HFNC) 氧气治疗是一种潜在的替代方案,但其在降低老年COPD患者的再灌输率方面的有效性尚不清楚.
研究的目的:
- 为了探索HFNC的安全性和有效性,与NIV相比,在拔后对老年COPD患者进行治疗.
- 为了评估HFNC在减少72小时和7天后的再输入管率方面的非劣势.
主要方法:
- 一个单中心,前性,非劣质,随机对照试验,涉及168名老年患者 (>65岁) 患有COPD在侵入性通风后.
- 患者将被随机分配,在输出管后立即接受HFNC或NIV.
- 主要结局包括72小时和7天的再灌输率;次要结局评估治疗失败,生理参数,患者舒适度,不良事件以及无呼吸器日和死亡率等临床结局.
主要成果:
- 本部分应在研究完成后填写.
- 将收集和分析关于再灌输率,患者舒适度,不良事件和临床结果的数据.
结论:
- 这项研究将提供关于HFNC与NIV在老年COPD患者脱口术后的比较有效性和安全性的关键证据.
- 这些发现将为在这个脆弱的患者群体中提供呼吸支的临床实践指南提供信息.
相关概念视频
Administering Oxygen by Nasal Cannula
407
Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations.
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
407
Oxygen Delivering System I: Nasal Cannula and Face Mask
247
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
247
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
379
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
379
Mechanical Ventilation III: Noninvasive Ventilation
81
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
Noninvasive Positive-Pressure Ventilation...
81
Administering Oxygen by Mask
252
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
252
Tracheostomy Decannulation
122
Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
122


