在急诊室使用抗微生物表面涂层作为感染控制的保护技术 (ASEPTIC):试点随机对照试验
Lenard Cheng1,2, Shun Yee Low3,4, Yuru Boon5,6
1Emergency Medicine Department, National University Hospital, National University Health System, Level 4, National University Centre for Oral Health Singapore (NUCOHS), 9 Lower Kent Ridge Road, Singapore, 119085, Singapore. lenard_cheng@nuhs.edu.sg.
Antimicrobial resistance and infection control
|October 29, 2024
概括
一种抗微生物表面涂层在24小时内显著减少了急诊室 stretcher 轨道上的细菌. 这项试点研究评估了高触摸表面的持续消毒,显示了感染控制的初步承诺.
科学领域:
- 感染控制 感染控制
- 微生物学 微生物学
- 表面科学是一门学科.
背景情况:
- 医疗机构的高触频表面存在病原体传播的风险.
- 应急部门 (ED) 的杆经常被接触,需要有效的消毒策略.
研究的目的:
- 评估抗微生物表面涂层对ED中高触频表面的连续消毒的有效性.
- 评估与安慰剂对抗微生物涂层处理的 stretcher 轨道上的细菌污染水平.
主要方法:
- 一项试点随机对照试验在ED的96个担架轨道上进行.
- 轨道被随机分配到接受抗微生物涂层或安慰剂涂层,并继续进行例行清洁.
- 细菌采样 (总有氧,基阳性,基阳性,基阴性,MRSA) 在基线,治疗后24小时,7天和180天进行.
主要成果:
- 抗微生物药物和安慰剂组之间的基线细菌水平是可比的.
- 在24小时后,与安慰剂轨道相比,抗微生物涂层轨道上的有氧细菌污染总量明显较低 (0.61对1.01CFU/cm2).
- 虽然污染在7天后往往较低,但在180天后更高,尽管这些差异在统计学上并不显著.
结论:
- 这是第一个双盲,安慰剂控制,随机化试验,评估ED高触摸表面的抗微生物表面涂层.
- 抗微生物涂层显示,在施加后24小时内, stretcher 轨道上的有氧细菌总量显著减少.
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