迷幻药物与其他物质的同时使用:全球迷幻调查的调查结果
Stephanie Lake1,2, Philippe Lucas3
1UCLA Center for Cannabis and Cannabinoids, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA.
Journal of psychopharmacology (Oxford, England)
|October 29, 2024
概括
迷幻药的共同使用是常见的,特别是在娱乐用途. 降低危害策略应针对特定的迷幻药物使用者和物质,以减轻与组合物质相关的潜在风险.
科学领域:
- 精神活性物质研究 精神活性物质研究
- 公共卫生 公共卫生
- 神经科学是一个神经科学.
背景情况:
- 迷幻药一般具有较低的危害风险,但与其他物质共同使用可能会增加健康和社会危害.
- 了解迷幻药的共同使用模式对于降低危害至关重要.
- 这项研究全面描述了大型国际样本中迷幻药的共同使用.
研究的目的:
- 描述迷幻药的共同使用的流行,模式和动机.
- 确定与共用相关的社会人口统计学和迷幻药物使用相关的因素.
- 为心理迷幻药品使用者提供有针对性的减害策略.
主要方法:
- 利用了2023年全球迷幻调查的数据,这是对21岁以上终身迷幻药物使用的成年人进行的基于网络的调查.
- 分析了共同使用的模式,包括流行率,二次物质,时间和动机.
- 检查了社会人口统计学因素,迷幻药的使用特征,以及整体和特定迷幻药的共同使用之间的关联.
主要成果:
- 在5370名受访者中,超过一半 (56.3%) 报告说他们同时使用迷幻药物,其中氧化的比例最高 (54.5%),亚亚瓦斯卡的比例最低 (14.8%).
- 大麻和酒精是最常见的次要物质;抑郁药在迷幻后的使用中显著增加.
- 更大的迷幻体验,娱乐动机和物质替代与共同使用有关;个人探索和治疗动机与负相关.
结论:
- 观察到大量的共用迷幻药,特别是有娱乐意图的共用.
- 调查结果确定了特定的用户群体和物质,以提供量身定制的减少危害信息.
- 需要进一步的研究来确定特定的共同使用模式是否会减轻或加剧潜在的危害.
更多相关视频
相关概念视频
CNS Stimulants: Psychedelic Agents
127
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
127
Hallucinogens and Psychedelics
157
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
157
Altered States of Awareness
156
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
156
An Overview of Psychoactive Drugs
195
Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
195
Combined Effects of Drugs: Synergism
3.7K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
3.7K
Combined Effects of Drugs: Antagonism
8.3K
The combined effects of drugs can result in various interactions, of which an important type is antagonism. Antagonism is a mechanism where one drug inhibits or counteracts the effects of another drug. Antagonism can occur through various means, including receptor binding, allosteric modulation, functional interaction, chemical reactions, and pharmacokinetic processes.
The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
8.3K


