相关实验视频
Updated: Jun 9, 2025

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
18.8K
在癌症患者中治疗葡萄糖皮质激素诱导的高血糖症:可行性研究
Jenny Wright1, Theresa Nielsen1, Samantha Burns1
1Bankstown-Lidcombe Hospital, NSW, Australia.
Clinical nursing research
|October 29, 2024
概括
一个由护士领导的模型,用于在癌症患者中管理葡萄糖皮质激素诱导的高血糖症 (GIH),显示出可行性,但在血糖监测方面面临着坚持挑战. 在高剂量葡萄糖皮质醇治疗期间,需要采用替代策略来有效管理GIH.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
- 护理 护理 护理
背景情况:
- 葡萄糖皮质类药物在癌症治疗中至关重要,但可能导致高血糖,增加患者的发病率.
- 葡萄糖皮质类药物诱导的高血糖 (GIH) 是患有血液和固体恶性瘤的患者的一个重大问题.
- 有效的GIH查和管理对于优化癌症护理至关重要.
研究的目的:
- 评估护士领导的护理模式 (MOC) 的可行性和可接受性,用于查和管理GIH.
- 评估患者和卫生专业人员与MOC的经验.
- 确定癌症患者的GIH管理的挑战和潜在改进.
主要方法:
- 一个单位可行性研究,涉及接受高剂量葡萄糖皮质激素 (HDG) 的非糖尿病癌症患者.
- 在葡萄糖皮质类药物治疗 (GT) 期间,患者使用血糖计自我监测血糖水平 (BGLs).
- 通过同意率,完成率和患者/工作人员调查来评估可行性;进行了GIH查.
主要成果:
- 48%的接触患者同意;没有人有先前存在的糖尿病.
- 13%的患者患有肠道胃炎;遵守BGL监测是一个重要问题.
- 临床利益相关者认为MOC是可行的和可接受的,尽管监测存在挑战.
结论:
- 护士领导的MOC是可行的查GIH在癌症患者在HDG.
- 自我监测BGLs提出了坚持挑战,影响MOC的可持续性.
- 对GIH监测和管理的替代方法需要探索以改善遵守和结果.
更多相关视频
相关概念视频
Hypoglycemia and Glucagon
153
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
153
Diabetes: Management and Pharmacotherapy
237
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
237
Oral Hypoglycemic Agents: Biguanides and Glitazones
176
Biguanides, particularly metformin (Glucophage), are insulin sensitizers that enhance glucose uptake, thereby reducing insulin resistance. Unlike sulfonylureas, metformin doesn't prompt insulin secretion, which helps to curb hypoglycemia risk. Metformin is beneficial in treating conditions like polycystic ovary syndrome due to its insulin-resistance reduction capability. The drug's primary action involves curtailing hepatic gluconeogenesis, a significant contributor to high blood...
176
Oral Hypoglycemic Agents: α-Glucosidase Inhibitors
161
α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...
Acarbose and miglitol are...
161
Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Oral Hypoglycemic Agents: Glinides
142
Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively...
142

