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Updated: Jun 9, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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抗精神病药物的肝毒性:一项探索性药理流行病学和药理动力学研究,整合了FAERS数据和体外受体结合相似性

René Zeiss1, Carlos Schönfeldt-Lecuona1, Bernhard J Connemann1

  • 1Department of Psychiatry and Psychotherapy III, University of Ulm, Ulm, Germany.

Frontiers in psychiatry
|October 29, 2024
PubMed
概括

抗精神病药物可以导致药物诱导性肝损伤 (DILI). 这项研究将DILI风险与特定的受体相互作用联系起来,表明血清醇和胆固醇系统可能参与抗精神病性肝毒性.

关键词:
抗精神病剂是一种抗精神病剂.化学和药物诱导的肝损伤.药物监督和药物监督结合受体与受体的结合方式血清素受体是血清素的受体.

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