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Updated: Jun 9, 2025

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
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下一代测序确定了两个新的HLA-B等位基因,HLA-B*37:113和HLA-B*41:02:12

Maria Loginova1,2, Ivan Obukhov1, Igor Paramonov1

  • 1Federal State Budget Research Institution, Kirov Hematology and Blood Transfusion Research Institute Under the Federal Medicine and Biology Agency, Kirov, Russia.

HLA
|October 29, 2024
PubMed
概括

使用下一代测序 (NGS) 发现了两个新的人类白细胞抗原B (HLA-B) 基因,HLA-B*37:113和HLA-B*41:02:12. 这一发现有助于对HLA-B遗传多样性的日益增长的理解.

关键词:
HLA-B*37:113 这种情况是什么?HLA-B*41:02:12 这是一个很好的方法.没有NGS,没有NGS.一个新的等位基因.

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相关概念视频

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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