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Updated: Jun 9, 2025

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
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一种新型的 metionyl-tRNA 合成酶抑制剂,向阳性细菌病原体

Nora M R Molasky1, Zhongsheng Zhang2, J Robert Gillespie1

  • 1Center for Emerging and Re-emerging Infectious Diseases, Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, Washington, USA.

Antimicrobial agents and chemotherapy
|October 29, 2024
PubMed
概括

一种新的抗生素MRS-2541,有效地向像金黄色葡萄球菌 (Staphylococcus aureus) 这样的阳性细菌. 这种新型的metionyl-tRNA合成酶抑制剂在临床前模型中显示出治疗皮肤和软组织感染的前景.

关键词:
这种病原体是葡萄球菌.抗生素 抗生素是一种抗生素.发现药物的发现.在tRNA合成过程中

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