读者间协议对对比度增强的超声波肝脏成像报告和数据系统的主要特征和最终分类:从前性多中心研究的子分析
Cristina M Kuon Yeng Escalante1, Tania Siu Xiao1, Yuko Kono2
1Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
概括
与对比度增强的超声波 (CEUS) 肝脏成像报告和数据系统 (LI-RADS) 显示了对诊断肝细胞癌 (HCC) 的实质性协议. 这证实了CEUS LI-RADS作为高危患者HCC诊断的可靠工具.
科学领域:
- 放射学 放射学是一门学科.
- 肝病学 肝病学是一种肝病学.
- 在瘤学瘤学.
背景情况:
- 与肝脏成像报告和数据系统 (LI-RADS) 结合的对比增强超声波 (CEUS) 对于诊断高风险个体的肝细胞癌 (HCC) 至关重要.
- 之前验证CEUS LI-RADS在北美和欧洲患者队列中的读者间变异性是有限的.
研究的目的:
- 评估CEUS LI-RADS特征的读者间协议和HCC的最终分类.
- 在北美和欧洲患者群体中验证CEUS LI-RADS的可靠性.
主要方法:
- 一个涉及150个肝结节的跨国前性研究数据库的回顾性分析.
- 由现场医生和盲目的中央读者进行评估,最终诊断通过复合参考标准得到确认.
- 使用科恩的kappa (κ) 统计学评估的读者间一致性.
主要成果:
- 对于整体的CEUS LI-RADS分类,观察到大量的读者间一致性 (κ = 0.61).
- 对主要特征 (κ = 0.640.78),LR-5 (κ = 0.65) 和LR-M (κ = 0.67) 类别而言,协议是实质性的.
- 在LR-1和LR-2类别中发现了近乎完美的一致性 (κ = 0.85).
结论:
- 这项研究表明,对于CEUS LI-RADS分类和主要的HCC成像特征,读者之间存在实质性的共识.
- 据证实,CEUS LI-RADS 是一种有价值和可靠的工具,用于在高危患者中诊断HCC.
- 结果支持在不同读者和中心一致应用CEUS LI-RADS.
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