美国减弱系数的系统间和运营商间协议,用于量化肝硬化症
Giovanna Ferraioli1, Davide Roccarina1, Richard G Barr1
1From the Department of Clinical-Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy (G.F.); Division of Internal Medicine and Hepatology, Azienda Ospedaliero Universitaria Careggi, Firenze, Italy (D.R.); Sherlock Liver Unit and UCL Institute for Liver and Digestive Health, Royal Free Hospital, London, England (D.R.); Department of Radiology, Northeast Ohio Medical University, Rootstown, Ohio (R.G.B.); and Southwoods Imaging, 7623 Market St, Youngstown, OH 44512 (R.G.B.).
超声波减弱系数 (AC) 测量肝肥症在不同系统之间显示出显著的变化,限制了它们在诊断中的可互换性. 然而,在各种交流算法中,运营商间的协议从中等到优秀不等.
科学领域:
- 医疗成像医学成像
- 诊断性的超声波检查
- 肝病学 肝病学是一种肝病学.
背景情况:
- 肝脏肥胖症的评估使用超声波衰减系数 (AC) 算法.
- 对于这些测量,关于系统间和运营商间变量的数据有限.
研究的目的:
- 评估超声波交流测量中系统间和运营商间的协议,以量化肝脂肪.
- 评估AC算法结果与MRI质子密度脂肪分数 (PDFF) 的相关性.
主要方法:
- 一项前性研究,涉及26名不同程度的肝硬化症患者.
- 两个操作员独立测量了AC,使用八种不同的超声波系统与制造商特定的AC算法.
- 在同一天,MRI PDFF测量由另一个操作人员执行.
- 类内相关系数 (ICC) 用于评估一致性;用于相关性分析的混合效应模型.
主要成果:
- 在五种算法中观察到美国AC和MRIPDFF之间的高相关性 (r=0.70-0.86),两个算法中适度 (r=0.62);一个算法中差 (r=0.47).
- 总体上,系统间协议很差 (ICC=0.33),系统对之间存在很大的变化.
- 互操作协议从中等到优秀 (ICC=0.50-0.90) 不同,三星医疗,西门子医疗和佳能医疗系统显示良好到优秀的协议.
结论:
- 在不同的超声系统中,AC值存在实质性的变化,这阻碍了肝硬化症诊断和监测的可互换性.
- 对交流测量的运营商间协议通常是很好或很好,这表明运营商的一致性是可以实现的.
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