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Updated: Jun 24, 2026

From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
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成年人骨的原发性扩散性大B细胞淋巴瘤:一个基于SEER人口的SEER研究

Jing Li1, Xiangpeng Li, Tong Gao

  • 1Department of Clinical Pharmacy, Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Medicine
|October 29, 2024
PubMed
概括

这项研究确定了原发性骨扩散性大B细胞淋巴瘤 (PB-DLBCL) 的临床特征和生存率. 开发的诺姆图准确预测患者的存活率,有助于优化这种罕见淋巴瘤的治疗.

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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
Cancers Originate from Somatic Mutations in a Single Cell02:21

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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...