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Updated: Jul 25, 2026

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry
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开发具有受约束形状的堆式适合体,用于骨质生成不完善的治疗方法

Gubu Amu1,2, Ge Zhang3,4, Nannan Jing5

  • 1Department of Clinical Pharmacy, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Journal of medicinal chemistry
|October 29, 2024
PubMed
概括

一种新的阿普坦稳定策略增强了亲和力和稳定性,通过促进骨生长来治疗骨质不完美的产生. 这种方法提高了以阿普坦为基础的药物的治疗潜力.

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相关概念视频

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.