来自鱼类,软体动物和甲动物的甲素的抗菌功能:一篇综述
Qing Song1, Qiaoying Li2, Yao Yang2
1Strait Institute of Flexible Electronics (SIFE, Future Technologies), Fujian Key Laboratory of Flexible Electronics, Fujian Normal University and Strait Laboratory of Flexible Electronics (SLoFE), Fuzhou 350117, Fujian, China.
Journal of agricultural and food chemistry
|October 29, 2024
概括
盖लेक्ट因是水生动物的关键免疫蛋白,与细菌和病毒作斗争. 了解它们的作用为保护养殖鱼类和贝类免受疾病提供了新的途径.
科学领域:
- 海洋生物学 海洋生物学
- 免疫学 免疫学 免疫学
- 生物化学 生物化学
背景情况:
- 甲状腺素是一种β-甲状腺素结合蛋白的家族,对脊椎动物和无脊椎动物的先天免疫力至关重要.
- 最近的研究突出显示了 galectins 在水生生物中的新兴作用.
- 这些蛋白质作为免疫防御中的模式识别受体起作用.
研究的目的:
- 审查最近在水生动物中的 galectins 的理解方面取得的进展.
- 探索抗微生物机制,分子结构和鱼类,软体动物和甲类动物中甲素的演变.
- 确定加勒素在水产养殖中的疾病控制方面的潜力.
主要方法:
- 关于水生生物中甲素研究的文献综述.
- 分析报告的抗微生物活性,包括细菌结合和生长抑制.
- 检查分子结构和 galectins 的进化关系.
主要成果:
- 水生加勒素对细菌表现出强大的抗菌活性.
- 它们增强免疫细胞的细胞形成,并促进抗病毒防御.
- 研究揭示了不同水生物种中加勒的多样化分子结构和进化路径.
结论:
- 黄素是水生动物天生的免疫系统的关键组成部分.
- 它们的抗微生物特性为水产养殖疾病管理提供了新的机会.
- 对加勒素功能的进一步研究可以导致创新的生物安全策略.
相关概念视频
Antimicrobial Proteins
939
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
939
Glycocalyx and its Functions
3.7K
The glycocalyx is a carbohydrate-rich, fuzzy-appearing layer on the outer surface of the cell membrane. It is highly hydrophilic, because of this it attracts large amounts of water to the cell's surface. This aids the cell's interaction with the watery environment and also helps it to obtain substances dissolved in the water. It is also important for cell identification, self/non-self determination, and embryonic development and is used in cell-to-cell attachments to form tissues.
3.7K
Gene Regulation in Microbial Communities: Quorum Sensing
3
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
3
Glycosaminoglycans
4.7K
Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
4.7K
Biological Methods for Microbial Control
2
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
2
Proteoglycans
3.9K
Glycans, a class of complex heterogeneous molecules, can be covalently attached to proteins to form glycosylated proteins that regulate various physiological and pathological processes. Glycosylated proteins or glycoproteins comprise N-linked and O-linked oligosaccharides. O-glycosylation is the most common type of protein glycosylation. Here, glycans attach to the oxygen atom of the hydroxyl groups of Serine or Threonine residues. O-linked glycosylation occurs later in protein processing,...
3.9K


