童年不良经历与认知衰退之间的关联:来自行为风险因素监测系统的发现,2015-2016年
Gaurav Chaudhari1, Darshini Vora1, Chintan Trivedi1
1Department of Psychiatry, Texas Tech University Health Science Center at Permian Basin, Midland, Texas.
The Journal of nervous and mental disease
|October 29, 2024
概括
儿童不良经历 (ACE) 与成人主观认知衰退 (SCD) 的增加有关. 较高的ACE数量显著增加了在以后的生活中经历认知衰退的几率.
科学领域:
- 精神病学是一个精神病学.
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 童年不良经历 (ACE) 是普遍存在的,并具有长期的健康影响.
- 主观认知衰退 (SCD) 影响了成年人口的很大一部分.
- 在ACE和成人认知衰退之间的关系需要进一步的研究.
研究的目的:
- 检查45岁及以上成年人的不良童年经历 (ACE) 和主观认知衰退 (SCD) 之间的关联.
- 量化与经历过的ACE数量相关的SCD风险.
主要方法:
- 对大型成人调查数据集 (N = 3900) 的分析.
- 使用后勤回归,赔率比率和95%的置信区间来评估ACEs-SCD关联.
- 在患有ACE和没有ACE的个体之间比较了SCD的患病率.
主要成果:
- 与没有ACE的成年人相比,报告至少有一次ACE的成年人中SCD的患病率明显高 (16.5%与8.1%,p<0.001).
- 在ACE和SCD数量之间发现了显著的正相关性 (p < 0.001).
- 经历SCD的几率与ACE的数量成比例增加.
结论:
- 童年不良经历与成年人主观认知能力下降的风险增加有显著的关联.
- 这些发现强调了解决童年逆境对于长期认知健康的重要性.
- 建议对更大种群进行进一步的研究,并控制混因素.
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