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Updated: Jun 9, 2025

A Simple and Efficient Method for In Vivo Cardiac-specific Gene Manipulation by Intramyocardial Injection in Mice
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黑色素通过抑制PGAM5-mPTP通路来减轻肝脏缺血-再输液损伤

Xiaoyi Shi1,2,3, Jiakai Zhang1,2,3, Jie Gao1,2,3

  • 1Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.

PloS one
|October 29, 2024
PubMed
概括

黑素通过阻断PGAM5-mPTP通路来保护肝细胞免受损伤,而PGAM5-mPTP通路在缺血-再输液 (I/R) 损伤期间被激活. 这一发现为治疗肝脏I/R损伤提供了一种新方法.

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Management of Insomnia01:19

Management of Insomnia

The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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