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Updated: Jun 9, 2025

Study of the DNA Damage Checkpoint using Xenopus Egg Extracts
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Study of the DNA Damage Checkpoint using Xenopus Egg Extracts

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激酶ATR控制了Arabidopsis在基因组尺度上的介质交叉分布

Longfei Zhu1, Julia Dluzewska1, Nadia Fernández-Jiménez2

  • 1Laboratory of Genome Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University in Poznan, 61-614 Poznan, Poland.

The Plant cell
|October 29, 2024
PubMed
概括

ATAXIA-TELANGIECTASIA AND RAD3-RELATED (ATR) 激酶失活在Arabidopsis重组介质交叉分布,增加在染色体臂和减少在周心体,而不改变DNA双链断裂数.

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An Efficient Method for Quantitative, Single-cell Analysis of Chromatin Modification and Nuclear Architecture in Whole-mount Ovules in Arabidopsis

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DNA Damage can Stall the Cell Cycle

In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
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Meiosis II entails cell division and segregation of the sister chromatids, resulting in the production of four unique haploid gametes. The steps for meiosis II are similar to mitosis, except that meiosis II occurs in haploid cells, whereas mitosis occurs in diploid cells.
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Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
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M cyclin...
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