结核病中的性结核病:美国30年的经验
Yevgen Chornenkyy1, Masa Peric1, David Marin Flores2
1Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
性肠炎 (UE) 是一种罕见的乳性疾病并发症,存在阻塞和出血的风险. 对UE的治疗结果是可变的,死亡率很高,需要进一步研究有效的管理策略.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
背景情况:
- 性结核炎 (UJ) 或性肠炎 (UE) 是乳病 (CeD) 的罕见并发症.
- 缺乏UE的诊断和管理指南.
- 在美国,UE的病例报告有限.
研究的目的:
- 描述性肠炎患者的临床表现,诊断,治疗和结局.
- 评估UE不同治疗方式的疗效.
- 为了确定这个并发症的适当术语.
主要方法:
- 在美国的一个大型学术中心进行了一系列案例.
- 收集的数据包括临床表现,诊断结果,治疗干预措施和疾病演变.
- 鉴定和分析了8例带有UE的CeD病例.
主要成果:
- 介绍包括肠道阻塞,肠道出血和吸收不良.
- 在十二指肠中发现了,并且仅仅超出了Treitz的角度,支持了UE的术语.
- 用皮质类固醇治疗是无效的;手术切除和cladribine显示出不同的结果. 两名患者患有肠病相关的T细胞淋巴瘤,整体死亡率为50%.
结论:
- 性肠炎是乳病的严重并发症,具有阻塞和出血的高风险.
- 皮质类固醇对UE无效.
- 治疗结果是可变的,死亡率很高,需要进一步的研究.
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