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Updated: Jun 9, 2025

Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo
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在异形性肺纤维化中准PI3K/mTOR通路:进展和治疗潜力

Zhengyang Wang1, Yanzhi Guo1, Kaiyin Li1

  • 1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.

Bioorganic & medicinal chemistry
|October 29, 2024
PubMed
概括

针对酸-3-酶 (PI3K) /哺乳动物目标的拉巴胺素 (mTOR) 途径的新疗法在治疗异常性肺纤维化 (IPF) 方面显示出前景. 这些PI3K/mTOR抑制剂可能为IPF患者提供更好的结果.

关键词:
原沉积的结合物沉积.异形性肺纤维化症 异形性肺纤维化症在PI3K/mTOR信号通路中,有针对性的治疗.

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